Any ROP Risk Calculator

Intended moment of prediction: Enter information available when the treating neonatologist requests or schedules the first planned ophthalmologic examination

Predictor information

Birth weight (grams)

Gestational age at birth

Completed weeks

Additional days, 0–6

Converted internally to total gestational days before prediction

Cumulative oxygen exposure (days)

Mechanical ventilation via endotracheal tube (days)

Multiple gestation

Respiratory distress syndrome

Neonatal sepsis

Necrotizing enterocolitis

Neonatal anemia

Bronchopulmonary dysplasia

Predicted probability of any ROP —

Model equation and technical information

Gestational age is entered as completed weeks plus additional days and converted internally as: total gestational days = 7 × weeks + additional days


              logit(p) = 12.59273
              − 0.0025779 × birth weight (g)
              − 0.0595762 × gestational age (days)
              + 0.0268105 × oxygen exposure (days)
              − 0.0191566 × endotracheal tube duration (days)
              − 0.0774483 × multiple gestation
              − 0.0658395 × respiratory distress syndrome
              + 0.3479630 × neonatal sepsis
              − 0.2764242 × necrotizing enterocolitis
              − 0.0290614 × neonatal anemia
              − 0.2715983 × bronchopulmonary dysplasia

The primary exploratory threshold is 7.34%, corresponding to the prevalence of any ROP in the development cohort. A secondary 2.20% threshold is displayed for comparison with the literature

Observed event proportions shown in the result panel describe the corresponding model-defined groups in the development cohort. They are not the infant's individual predicted probability and require external validation